Well I just have to say yes experiment and everyone has different hands, skin, and fingers, This means that even if you really want to use a
Certain size set of strings, you may not be able to adapt. In theory thicker strings sound bigger, stay in tune better, have more sustain, and
Don't break as much as thin strings. But most famous rock players use a .009 or .10 set , because they may be doing a lot of vibrato,
string-bending, hammer-ons, and very fast playing. And if you are playing for 2hrs doing solos in every song, trying to use a .11 set
Or higher is very likely going to tear your skin off. Well, maybe not, but few can do this.